Sanctions Compliance: 7 Best Practices Every Business Should Follow

COMPLIANCE TIPS & BEST PRACTICES

8/18/2025

In today’s fast-moving regulatory environment, sanctions compliance isn’t optional — it’s essential. With the rise of global conflicts, shifting political alliances, and expanding regulatory frameworks, organizations of all sizes are facing greater pressure to ensure they don't violate international sanctions laws.

Whether you’re a bank, fintech, logistics company, or multinational corporate, these seven best practices will help you strengthen your sanctions compliance framework and stay one step ahead of risk.

1. Start with a Risk-Based Approach

Not all sanctions risks are equal. Your first step should be to understand where your business is most exposed, whether through geography, customer base, supply chain, or products. A sanctions risk assessment provides a clear picture of your threat landscape and helps tailor your controls accordingly.

2. Build a Strong Policy Framework

A clear, well-documented sanctions compliance policy sets the foundation for your program. It should define roles, responsibilities, escalation paths, and how your business addresses key risk scenarios. Make sure it’s regularly reviewed and aligned with the latest regulatory expectations.

3. Invest in Effective Screening

Robust screening tools are essential but they’re only as good as the data and logic behind them. Review and tune your screening settings regularly, and ensure you’re screening against the most up-to-date lists from OFAC, OFSI, EU, UN, and other relevant bodies.

4. Don’t Overlook Data Quality

Bad data leads to bad outcomes. Poor customer or third-party data can result in missed hits or false positives. Make sure your onboarding, KYC, and vendor management processes support clean, structured, and sanctions-relevant data.

5. Train Your People

Compliance is a team sport. Tailored training, not just generic e-learning that helps staff across business lines understand what sanctions mean, how to spot red flags, and how to escalate concerns appropriately.

6. Monitor Regulatory Change

Sanctions regimes change fast. Subscribe to trusted sources (like ComplySphere Insights 😉) and assign responsibility for tracking changes in real-time. Build agility into your compliance process so you can respond quickly when updates hit.

7. Review and Test Regularly

Conduct internal reviews or external health checks to ensure your program is fit for purpose. Testing your screening tools, alert-handling processes, and governance controls helps identify blind spots before regulators do.

Final Thoughts

Sanctions compliance isn’t just about ticking boxes, it’s about protecting your business from financial, legal, and reputational harm. By embedding these best practices into your program, you can build a more resilient, responsive, and confident compliance culture.

Need help reviewing or strengthening your sanctions program? Contact ComplySphere for a free sanctions assessment — let’s simplify compliance, together.